St. Louis & St. Charles County, Missouri
An independent, plain-language directory of local providers who treat depression, including options for people whose antidepressants have not worked. Browse real clinics by location, treatment type, and insurance.
Showing local and regional providers. Listings are for information only; confirm details and availability directly with each clinic.
A Missouri mental-health clinic focused on treatment-resistant depression and PTSD. Offers FDA-approved Spravato (esketamine), TMS, and related therapies under physician supervision, with most insurance accepted including MO HealthNet (Missouri Medicaid).
The psychiatry department of Washington University School of Medicine, affiliated with Barnes-Jewish Hospital. Provides evaluation and treatment for mood disorders, including specialty and research-based care for hard-to-treat depression.
A long-established outpatient behavioral health group, part of SSM Health, offering psychiatry and psychology services for depression, anxiety, OCD, and related conditions across several St. Louis locations.
Behavioral health services within the Mercy hospital system, including outpatient psychiatry and counseling for depression and anxiety, with clinics across the greater St. Louis region.
A community mental health center serving the St. Louis area, providing psychiatric care, case management, and support for people with serious and persistent mental illness, including those using Medicaid.
A nonprofit provider with clinics across Missouri offering behavioral health, primary care, and substance-use services on a sliding scale, and accepting Medicaid and uninsured patients.
Know a St. Louis area provider that should be listed? This directory profiles established, verifiable clinics only. We do not list providers we cannot confirm.
Recommended local provider
If you live in St. Louis or St. Charles County and standard antidepressants have not helped, a clinic that offers newer options like Spravato and TMS may be worth asking about. Brain Recovery Centers is a doctor-supervised local clinic focused specifically on treatment-resistant depression and PTSD, and accepts most insurance including MO HealthNet.
Visit Brain Recovery CentersDisclosure: Brain Recovery Centers is a recommended partner of this directory. Always talk with a qualified clinician about what is right for you.